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IMPOTENCE

Impotence is a consistent inability to sustain an erection, which is sufficient for sexual penetration. In medical terms it is known as Erectile Dysfunction. Impotence is different from other problems that interfere with sexual intercourse, for e.g. Lack of desire or difficulties with ejaculation or orgasm.





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PROCEDURES AND EFFECTIVENESS


How Does an Erection Occurs?

The two chambers that run the length of the penis are called corpora cavernosa. This tissue is spongy inside these compartments. Tunica albuginea is the membrane that envelops these corpora cavernosa. Vases, arteries, spaces, fibrous tissue, and smooth muscles are all present in the spongy tissue. Encircling the base of the corpora cavernosa lies the Urethra, a frequent conduit for semen and urine.

Mental and sensory stimulation precedes erection. The smooth muscles of the corpora cavernosa relax in response to brain and local nerve impulses, allowing blood to enter and fill the empty gaps. Consequently, the corpora cavernosa experiences pressure from the blood, causing the penis to become turgid.

An erection can be sustained thanks to the tunica albuginea’s role in retaining blood in the corpora cavernosa. When the penile muscles contract, the blood flow is stopped and outflow channels are opened, reversing the erection.

How is Impotency Caused?

A sequence of events is required to cause an erection and if at any stage, any break occurs, impotence results. The sequence of events is like – first of all nerve impulses generate in the brain, via spinal cord passes down around the penis and as a result produces response in muscles, fibrous tissues, veins and arteries in and around the corpora cavernosa.

The commonest cause of impotence is because of any damage to the fibrous tissues, veins, arteries smooth muscles etc. The diseases which affect these structures are diabetes, chronic smoking or tobacco, chronic alcoholism, kidney diseases, multiple sclerosis, atherosclerosis and vascular diseases generally responsible for about 65 – 70% of cases of impotence. Almost 35 – 50% of men suffering from diabetes, develop impotence.

Injury to the spinal cord, bladder, prostate, pelvis or penis can cause impotence by damage to the nerves, smooth muscle arteries and fibrous tissues of the corpora cavernosa. Also the surgery in pelvic area can damage nerves or blood vessels, results in impotence.

Long term use of many commonly used drugs like drugs for high blood pressure, antidepressants, tranquilizers, appetite suppressants, antacids and antihistaminics etc. can cause impotence as side effects.

About 30 – 35% of the cases of impotence are because of psychological reasons. These includes depression, anxiety, stress, guilt, fear of being caught, fear of failure, lack of correct sex knowledge, myths and misconceptions regarding sex. These factors are generally associated with more than 80% of the cases of Impotence.

Causes of Impotency

Performance Anxiety

This is a psychogenic problem. Erection is not possible for a man who is anxious and or depressed. Stressful conditions cause liberation of Catecholamines such as (Adrenaline and nor-adrenaline) which stops erection.

Depression

This is an important cause of impotence. But unfortunately, most of the antidepressant medicines cause erectile failure. Thus reducing the patients depression by intensive counselling is the first line of treatment.

Organic Impotence

The most common cause of organic impotence is problems in Penile Arteries or Veins or both . In arterial cause, Arteriosclerosis or hardening of the arteries is the main cause. A Venous leak is the most common vascular cause. In a normal man, arterial inflow increases to 5 to 10 times during sexual excitement. As a result the Venous drainage get compressed temporarily, thus sustaining erection. When this drainage system becomes weak and cannot hold the blood back, the penis becomes soft and flaccid. This is the result of Venous leak.

Associated factors like overweight, lack of exercise, tobacco, smoking, hyperlipidaemia, high blood pressure etc. all will leads to early erectile failure often before progressing to affect the heart. The Penile arteries are about 1/3rd the size in diameter of the Coronaries arteries and therefore the Penile arteries gets chocked sooner. Remember , if the person changes his life style well in time, these changes are reversible.

Diabetes and Impotence

Impotence is most common in diabetics. It is estimated that about 50% of the diabetics are impotent and the rest will become impotent with time. This is usually due to premature hardening of the arteries. Peripheral Neuropathy with involvement of nerves controlling erection is common in diabetics.

Neurological causes of Impotence

There are many reasons for the neurological causes of impotence. Chronic alcoholism, diabetes, multiple sclerosis, heavy metal poisoning, spinal cord injuries and injuries to nerves by Pelvic trauma, injuries of surgery, all can lead to erectile dysfunction.

Drugs and Impotence

Commonly used drugs like antidepressant, antihypertensive, antianxiety, glucoma eye drops and chemotherapy agents are few of the many drugs which can lead to impotency. Therefore the drugs should be taken under strict medical supervision.

Hormone Induced Impotence

Increased Prolactin(produced by anterior Pitutory), steroid abuse by body-builders, more or less levels of thyroid and hormonal drugs administered for prostatic cancer may cause impotence. Rarely low level of testosterone can cause impotence.

Anatomical defects

Sometimes Cogenital or acquired abnormalities of the penis may prevent erection. For eg – Peyronies Disease or Chordaee etc.

Cogenital Venous Leak

In this condition, closure of Venous Valve do not occur, which is a must for the engorgement and rigidity of the penis. Therefore such men cannot get a rigid erection and penile axial pressure is low and results in Impotence.

Causes of Impotency

How to Diagnose Impotency?

  • A detailed history revealed by the patient is the best diagnostic method. A brief medical and sexual history helps to diagnose type and degree of impotence.
  • A thorough physical examination.
  • Laboratory tests includes: Complete Blood Count, Blood Sugar, Liver Functions Test, Lipid Profile, Renal Profile, Hormonal Analysis, Urine Examination etc.
  • Imaging Techniques.
  • P.T. monitoring (Nocturnal Penile Tumuscence).
  • Peno -Brachial- Index (P.B.I.).
  • Psycological evaluation (If needed also of the man’s sexual partner)

What are the recent Trends in the treatment of Impotency?

The treatment for impotence starts from non-invasive to most invasive

  • To reduce or cut down the doses of harmful drugs.
  • To Clear Myths and Misconceptions.
  • To impart correct Sex – Knowledge.
  • Psychotherapy and behavior modification.
  • Oral Drugs:
    • Yohimbine, Testosterone, Sildenafid (Viagra) etc .
  • Non-Invasive Procedures:
    • External Vaccum Device.
    • Trans Urethral Suppositories.
  • Hormone Replacement Therapy.
  • Intrapenile Cavernosal Injection Therapy.
  • Penile Implants (Prosthesis).
  • Surgery for Vascular Corrections.

Oral Drugs

Yohimbine:

It is obtained from the bark of the Yohimbehe tree. It’s side effects may be headache, excessive sweating , dizziness, nausea etc.

Testosterone:

An acute deficiency of male hormone, testosterone can cause impotence. The hormone should be replaced up to acceptable levels for effectiveness.

Sildenafil (Viagra):

It may enhances the erection by regulating vasodilatations in the penis but it neither cure impotence, nor increases libido.

Sidenafil is a known Phosphodiesterase5 (PDE5) inhibitor. By inhibiting the PDE5 enzyme, which is present mainly into the penis, Sildenafil allow the chemical produced during sexual stimulation, cyclic GMP, to persist. The longer cyclic GMP persists, the better chance for increased blood flow and hence an erection.

One suffering from Diabetes, High blood pressure, Cardiac problems, Sickle Cell Anemia, Bleeding Disorders, Multiple Myeloma, Gasteric Ulcers etc. should not take Sildenafil without medical supervision.

Newer drugs under research:

– VASOMAX

– TAP

– Oral Phentolamine

External Vaccum Device:

The External Vaccum Device with one or more rubber tension bands are used for the treatment. When the penis is not erect, it is placed in the vaccum chamber and then pump to produce an erection. Once the erection is achieved, the rubber tension band is slipped around the base of the penis as a result the outflow of blood from penis is stopped and penis remains engorged and hence erection. Band should not be kept around penis for more than 30 minutes to prevent the permanent damage to the penis.

Trans Urethral Suppository:

MUSE is a non – injectable delivery system for alprostadil, for the treatment of impotence. After Urination, a small applicator tip is inserted just over an inch in to the Urethra. A dose of Alprostadil, in the form of a suppository, is delivered by applicator. The drug is absorbed through the Urethral Wall i.e.,(Urethra Mucosa) As a result, relaxation of smooth muscles of penis occurs resulting in increased Penile blood inflow and thus rigidity. The action of the drug (MUSE) begins in 5- 10 minutes.

Hormone Replacement Therapy:

Impotence may also occur with the disturbance in the levels of hormones like Testosterone, Prolactin and Estrogen. This can be treated by replacing the hormone under strict medical supervision.

Intra Penile Cavernosal Injection Therapy:

This therapy produces a firm erection within few minutes and last for a longer time. Person can himself inject the medicine before play. It is almost painless. Several drugs are available which if injected directly in to the Corpora Cavernosa of the penis, would produce an erection with in a few minutes. The first drug used was Papavarine, secondly Phentolamine, an alpha blocker and later on Prostaglandin E1 as an additive.

Side Effects:

Pain, Priapism etc. Priapism is a condition in which one gets an unwanted, prolonged , painful erection. It is an medical emergency.


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Tips for preventing Impotence

  • Maintaining general health by diet and exercises.
  • Avoid alcohol, particularly before sexual encounters.
  • Do not consume animal fats, sugar, fried or junk food.
  • Avoid stress, strain.
  • Kegels exercises.
  • Under strict medical supervision, changing or reducing medications causing impotence.
  • If you are suffering from impotence consult an expert.
  • Remember sexual functions changes with age and one requires more stimulation for a longer period of time to achieve an erection.

Myths and Misconceptions regarding Impotence and Reality.

  • Myth: Not many men suffer from Impotence.
  • Reality: Almost 2-3 in every 10 men suffers from Impotence.
  • Myth: Once you are Impotent, there is no treatment or hope in future.
  • Reality: Impotence can always been treated by various means successfully.
  • Myth: Along with the aging, Impotence is likely to occur.
  • Reality: The treatments available today for Impotence are suitable for all age groups and therefore a person can enjoy sex irrespective of his age.
  • Myth: One should not tell anybody about his Impotence.
  • Reality: It is always advisable to talk to your partner or a qualified doctor.
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Dr. Mahesh Nawal is a one of the best sexologist Indore & laser proctologist consultant in Indore with an experience of more than 35 years, Dr. Nawal performed or all type of major surgery including laparoscopic general surgery reconstructive surgery.


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